AERIAL PART FERULA TENUISECTA ALTERNATIVE INDUSTRIAL RAW MATERIAL FOR THE PRODUCTION OF TEFESTROL SUBSTANCE

The main losses of tefestrol have been identified and the advantages disadvantages existing technology in production substance from aerial parts Ferula tenuisecta established. It was found that final product obtained by has a green color does not meet requirements Pharmacopoeia article. stage proposed extraction sum esters sesquiterpene alcohols part purification extract, allowing to subsequent obtain without color. shown use activated carbon makes it possible remove extract. To purify other accompanying substances, chromatographic separation on silica gel is under following conditions: ratio amount introduced into column sorbent 1 : 20; height sorption layer diameter 4 1; elution rate 35 l/h.m2. pharmacopoeial proposed, crystallization technical mixture ethyl acetate with hexane volume 3. Based results obtained, developed for obtaining tenuisecta. Using this 70.96% content raw material, according 33.9%.